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Anticancer Res. 2005 Nov-Dec;25(6B):3995-8.

Cytogenetic investigations in four canine lymphomas.

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  • 1Center for Human Genetics, University of Bremen, Leobener Strasse ZHG, 28359 Bremen, Germany.


Four cases of canine lymphoma are presented, including histological examination and cytogenetic investigation. The first case showed a derivative chromosome 13, the second case showed a clonal trisomy 8 and the third case showed a complex karyotype with a clonal trisomy 13 and additional clonal trisomies of the chromosomes 20, 30 and 37, as well as a non-clonal tetrasomy 9. Case four showed a single trisomy 2. Comparing these results with human hematopoietic malignancies, there are notable similarities between both species.

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