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Biochim Biophys Acta. 2006 Mar;1758(3):404-12. Epub 2005 Nov 9.

Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics.

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  • 1Institute of Molecular and Cellular Biology, UPR 9021 CNRS, 15 Rue RenĂ© Descartes, 67084 Strasbourg, France.

Abstract

Functionalized carbon nanotubes (f-CNT) are emerging as a new family of nanovectors for the delivery of different types of therapeutic molecules. The application of CNT in the field of carrier-mediated delivery has become possible after the recent discovery of their capacity to penetrate into the cells. CNT can be loaded with active molecules by forming stable covalent bonds or supramolecular assemblies based on noncovalent interactions. Once the cargos are carried into various cells, tissues and organs they are able to express their biological function. In this review, we will describe the potential of f-CNT to deliver different types of therapeutic molecules.

PMID:
16307724
[PubMed - indexed for MEDLINE]
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