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1: Br J Dermatol. 2005 Dec;153(6):1204-6.Click here to read Links

Plasma cell balanitis treated with tacrolimus 0.1%.

Moreno-Arias GA, Camps-Fresneda A, Llaberia C, Palou-Almerich J.

Centro Médico Teknon, Despacho 27, Vilana 12, 08190 Barcelona, Spain. 935893067@telefonica.net

BACKGROUND: Plasma cell balanitis or balanitis of Zoon (BZ) is a frequent diagnosis in mature men and lesions are generally localized on the glans but may involve the prepuce; its aetiology remains unknown. OBJECTIVES: To present our experience with tacrolimus 0.1% ointment in the treatment of two patients with BZ refractive to other topical treatments. PATIENTS AND METHODS: Two uncircumcised mature caucasian males were seen, both presenting with BZ; topical tacrolimus 0.1% ointment twice daily was prescribed in each case. RESULTS: Marked improvement of the lesions in both patients has been observed, with follow-up of 1 year and 10 months, respectively. CONCLUSIONS: Topical tacrolimus 0.1% ointment is an effective and safe treatment for BZ.

PMID: 16307659 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Tacrolimus (Prograf® )

    Tacrolimus is used along with other medications to prevent rejection (attack of a transplanted organ by the immune system of a person receiving the organ) in people who have received kidney, liver, or heart transplants. ...

  • Tacrolimus Topical (Protopic® )

    Tacrolimus ointment is used to treat the symptoms of eczema (atopic dermatitis; a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes) in patients who cannot use other medicat...

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