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Cont Lens Anterior Eye. 2004 Mar;27(1):3-8.

Relative primary adhesion of Pseudomonas aeruginosa, Serratia marcescens and Staphylococcus aureus to HEMA-type contact lenses and an extended wear silicone hydrogel contact lens of high oxygen permeability.

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  • 1Bausch & Lomb, 1400 N. Goodman St., RD&E, P.O. Box 0450, Rochester, NY 14603, USA.



To compare multiple strains of Pseudomonas aeruginosa and representative isolates of Staphylococcus aureus and Serratia marcescens for their relative primary adhesion to a high Dk silicone hydrogel lens (36% H2O) with that of a HEMA-type lens (58% H2O).


A radiolabeled cell procedure with a 2-h cell exposure was employed for enumerating bacteria on unworn and worn silicone hydrogel (balafilcon A) and HEMA-type (etafilcon A) hydrogel lenses.


The degree of primary adhesion of P. aeruginosa to 7-day worn balafilcon A lens was similar to the degree of adhesion to unworn balafilcon A lenses. The degree of primary adhesion by clinical strains to unworn balafilcon A lenses and etafilcon lenses was strain variable, but did not differ markedly for the two lenses with a given strain of P. aeruginosa. Relative to most of the pseudomonad strains, adhesion to the hydrogel lenses by S. aureus and S. marcescens was non-significant.


Adhesion of strains of P. aeruginosa to a hydrogel contact lens does not appear to differ appreciably between the HEMA-type etafilcon A and the high Dk silicone hydrogel balafilcon A lens.

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