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Infect Immun. 2005 Dec;73(12):8407-10.

Clostridium perfringens enterotoxin damages the human intestine in vitro.

Author information

  • 1California Animal Health and Food Safety Laboratory-San Bernardino Branch, University of California-Davis, 105 W. Central Avenue, San Bernardino, CA 92408. mmiyakaw@cahfs.ucdavis.edu.

Abstract

In vitro, Clostridium perfringens enterotoxin (CPE) binds to human ileal epithelium and induces morphological damage concurrently with reduced short-circuit current, transepithelial resistance, and net water absorption. CPE also binds to the human colon in vitro but causes only slight morphological and transport changes that are not statistically significant.

PMID:
16299340
[PubMed - indexed for MEDLINE]
PMCID:
PMC1307077
Free PMC Article

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