Ned Tijdschr Geneeskd. 2005 Oct 29;149(44):2450-3.

[The foreskin and squamous-cell carcinoma of the penis].

[Article in Dutch]

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Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis, afd. Urologie, Plesmanlaan 121, 1066 CX Amsterdam. s.horenblas@nki.nl

Abstract

The incidence of penile cancer is low in men who have been circumcised at infancy. It is unknown whether a causative relationship exists between circumcision and the substantially reduced incidence of penile cancer. A normal foreskin has no known aetiological role in the development of penile cancer. A narrow, non-retractable foreskin predisposes the patient to infection and contributes to the development of penile cancer, together with the known risk factors of smoking and human papillomavirus infection. Circumcision represents a complex of social and behavioural factors. Analyses have not taken all of these factors into consideration. It is unlikely that circumcision itself protects against the development of penile cancer.

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Ned Tijdschr Geneeskd. 2005 Oct 29;149(44):2446-9.

PMID:: 16285359; [PubMed - indexed for MEDLINE]

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