[Receptor-mediated nongenomic action of thyroid hormone: T3-dependent activation of PI3K-->akt/PKB-->mTOR signaling cascade, leading to the upregulation of ZAKI-4alpha, a calcineurin inhibitor]

Nihon Rinsho. 2005 Oct:63 Suppl 10:16-9.

[Article in Japanese]

Authors

Hisao Seo¹, Xia Cao, Fukushi Kambe

Affiliation

¹ Department of Endocrinology & Metabolism, Research Institute of Environmental Medicine, Nagoya University.

PMID: 16279596

No abstract available

Publication types

Review

MeSH terms

Animals
Calcineurin Inhibitors*
Humans
Muscle Proteins / metabolism*
Phosphatidylinositol 3-Kinases / metabolism*
Phosphorylation
Protein Kinases / metabolism*
Proto-Oncogene Proteins c-akt / metabolism*
Receptors, Thyroid Hormone / physiology*
Signal Transduction / physiology*
TOR Serine-Threonine Kinases
Triiodothyronine / physiology*
Up-Regulation*

Substances

Calcineurin Inhibitors
Muscle Proteins
RCAN2 protein, human
Receptors, Thyroid Hormone
Triiodothyronine
Protein Kinases
MTOR protein, human
Proto-Oncogene Proteins c-akt
TOR Serine-Threonine Kinases