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Genome Biol. 2005;6(11):238. Epub 2005 Oct 31.

Virus-host interactions: new insights from the small RNA world.

Author information

  • 1Howard Hughes Medical Institute, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA. browne@saturn.med.nyu.edu

Abstract

RNA silencing has a known role in the antiviral responses of plants and insects. Recent evidence, including the finding that the Tat protein of human immunodeficiency virus (HIV) can suppress the host's RNA-silencing pathway and may thus counteract host antiviral RNAs, suggests that RNA-silencing pathways could also have key roles in mammalian virus-host interactions.

PMID:
16277756
[PubMed - indexed for MEDLINE]
PMCID:
PMC1297642
Free PMC Article

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