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1: Genome Biol. 2005;6(11):238. Epub 2005 Oct 31.Click here to read Click here to read Links

Virus-host interactions: new insights from the small RNA world.

Browne EP, Li J, Chong M, Littman DR.

Howard Hughes Medical Institute, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA. browne@saturn.med.nyu.edu

RNA silencing has a known role in the antiviral responses of plants and insects. Recent evidence, including the finding that the Tat protein of human immunodeficiency virus (HIV) can suppress the host's RNA-silencing pathway and may thus counteract host antiviral RNAs, suggests that RNA-silencing pathways could also have key roles in mammalian virus-host interactions.

PMID: 16277756 [PubMed - indexed for MEDLINE]

PMCID: PMC1297642