Large-scale approaches for glycobiology.
Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.
Glycosylation, the attachment of carbohydrates to proteins and lipids, influences many biological processes. Despite detailed characterization of the cellular components that carry out glycosylation, a complete picture of a cell's glycoconjugates remains elusive because of the challenges inherent in characterizing complex carbohydrates. This article reviews large-scale techniques for accelerating progress in glycobiology.
PMID: 16277754 [PubMed - indexed for MEDLINE]
PMCID: PMC1297640