Reprod Biomed Online. 2005 Oct;11(4):452-4.

Live birth after IVF in a 46-year-old woman.

Dal Prato L, Borini A, Cattoli M, Preti MS, Serrao L, Flamigni C.

Source

Tecnobios Procreazione, Centre for Reproductive Health, Via Dante 15, I-40125 Bologna, Italy. dalprato@tecnobiosprocreazione.it

Abstract

Pregnancies after IVF have been reported in women aged > or =44 years, but nobody older than 45 years at oocyte retrieval delivered. We report a case of birth of a healthy child after IVF in a 46-year-old infertile woman. Ovarian stimulation was performed with clomiphene citrate, 150 mg daily for 5 days. Three oocytes were retrieved and one embryo was replaced. The patient delivered a healthy male infant after Caesarean section at 39 weeks. A successful pregnancy after IVF with homologous oocytes can be achieved in women older than 45 years. At this age IVF is not a cost-effective treatment compared with oocyte donation, but it may be offered in countries in which gamete donation is forbidden.

PMID:: 16274607; [PubMed - indexed for MEDLINE]

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