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Science. 2005 Nov 4;310(5749):805-10.

Patterning and plasticity of the cerebral cortex.

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  • 1Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, 77 Massachusetts Ave., 46-6237, Cambridge, MA 02139, USA.


The cerebral cortex of the human brain is a sheet of about 10 billion neurons divided into discrete subdivisions or areas that process particular aspects of sensation, movement, and cognition. Recent evidence has begun to transform our understanding of how cortical areas form, make specific connections with other brain regions, develop unique processing networks, and adapt to changes in inputs.

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