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J Bacteriol. 2005 Nov;187(22):7863-5.

Streptococcus mutans murein hydrolase.

Author information

  • 1Department of Oral Biology, Indiana University School of Dentistry, Indianapolis, 46202, USA. dcatt@iupui.edu

Abstract

Allelic replacement of the C terminus of a Streptococcus mutans surface protein affects murein hydrolase activity. The targeted open reading frame encodes a 67-kDa protein (SmaA) with an N-terminal signal sequence and cleavage site, three 46-amino-acid (aa) direct repeats, and two 88-aa direct repeats. The identical autolytic profile was obtained using a sortase mutant (SrtA(-)).

PMID:
16267311
[PubMed - indexed for MEDLINE]
PMCID:
PMC1280295
Free PMC Article
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