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Nucl Med Commun. 2005 Dec;26(12):1107-11.

FDG PET imaging in the evaluation of post-transplant lymphoproliferative disorder following renal transplantation.

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  • 1Department of Radiology, Nottingham City Hospital, UK.

Abstract

OBJECTIVES:

To assess the usefulness of fluorodeoxyglucose positron emission tomography (FDG PET) in the evaluation of post-transplant lymphoproliferative disorder (PTLD) following renal transplantation.

METHODS:

Staging FDG PET examinations were reviewed in five patients with biopsy proven post-renal allograft PTLD and compared with conventional imaging. Follow-up PET examinations of three patients at various points during their therapy for PTLD were also reviewed and compared with clinical outcome.

RESULTS:

PET imaging identified all disease sites seen at cross-sectional imaging, clarified sites of uncertain significance and detected additional disease in two out of five patients. Early follow-up imaging impacted PTLD management in two of three patients.

CONCLUSION:

In this limited series FDG PET was an effective imaging modality in the staging and follow-up of PTLD.

PMID:
16264358
[PubMed - indexed for MEDLINE]
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