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    J Cell Biol. 2005 Nov 7;171(3):411-3. Epub 2005 Oct 31.

    Cytoplasmic dynein nomenclature.

    Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB.

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    Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA. kkp9w@virginia.edu

    Abstract

    A variety of names has been used in the literature for the subunits of cytoplasmic dynein complexes. Thus, there is a strong need for a more definitive consensus statement on nomenclature. This is especially important for mammalian cytoplasmic dyneins, many subunits of which are encoded by multiple genes. We propose names for the mammalian cytoplasmic dynein subunit genes and proteins that reflect the phylogenetic relationships of the genes and the published studies clarifying the functions of the polypeptides. This nomenclature recognizes the two distinct cytoplasmic dynein complexes and has the flexibility to accommodate the discovery of new subunits and isoforms.

    PMID:
    16260502
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC2171247
    Free PMC Article

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