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    Arq Neuropsiquiatr. 2005 Sep;63(3B):748-50. Epub 2005 Oct 18.

    Dexmedetomidine for awake craniotomy without laryngeal mask.

    Almeida AN, Tavares C, Tibano A, Sasaki S, Murata KN, Marino R Jr.

    Source

    Instituto Neurológico de São Paulo, Hospital São Joaquim, Real e Benemérita Sociedade Portuguesa de Beneficência, São Paulo, SP, Brasil. almeidaan@globo.com

    Abstract

    OBJECTIVE:

    This paper reports the use of dexmedetomidine in three epileptic patients with cavernous angiomas that underwent awake surgery in order to map their speech areas.

    METHOD:

    Loading dose of dexmedetomidine varied from 1 microg/Kg/h to 3 microg/Kg/h over 20 minutes and maintenance dose from 0.4 microg/Kg/h to 0.8 microg/Kg/h.

    RESULTS:

    There was no occurrence of hemodynamic instability, convulsions or respiratory depression. Patients tolerated well the procedure.

    CONCLUSION:

    Dexmedetomidine was useful for awake craniotomy as it decreased patients level of consciousness but did not produce agitation. Laryngeal mask was not necessary to keep air ventilation.

    PMID:
    16258649
    [PubMed - indexed for MEDLINE]
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