Format

Send to

Choose Destination
See comment in PubMed Commons below
Fitoterapia. 2005 Dec;76(7-8):722-4. Epub 2005 Oct 25.

Anticonvulsant evaluation of safranal and crocin from Crocus sativus in mice.

Author information

  • 1Pharmaceutical Research Center, Faculty of Pharmacy, Mashad University of Medical Sciences, Mashhad, Iran. hosseinzadehh@mums.ac.ir

Abstract

The anticonvulsant activities of Crocus sativus stigma constituents, safranal and crocin, were evaluated in mice using pentylenetetrazole (PTZ)-induced convulsions in mice. Safranal (0.15 and 0.35 ml/kg, i.p.) reduced the seizure duration, delayed the onset of tonic convulsions and protected mice from death. Crocin (200 mg/kg, i.p.) did not show anticonvulsant activity.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk