Severe rheumatoid valvular heart disease

Clin Rheumatol. 2006 Sep;25(5):743-5. doi: 10.1007/s10067-005-0039-7. Epub 2005 Oct 25.

Abstract

Rheumatoid arthritis (RA) is a systemic inflammatory disease in which extra-articular involvement is not uncommon. Cardiac compromise may be frequent, although most often, it is clinically silent. Herein, two cases of RA-related endocarditis, one of which required valve replacement, are described. Etanercept was useful in controlling the articular and extra-articular RA compromise in both cases.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antirheumatic Agents / therapeutic use
  • Arthritis, Rheumatoid / complications*
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / pathology
  • Captopril
  • Drug Therapy, Combination
  • Echocardiography
  • Endocarditis / complications*
  • Endocarditis / pathology
  • Endocarditis / therapy
  • Etanercept
  • Female
  • Heart Valve Diseases / complications*
  • Heart Valve Diseases / pathology
  • Heart Valve Diseases / therapy
  • Heart Valve Prosthesis Implantation
  • Humans
  • Immunoglobulin G / therapeutic use
  • Male
  • Middle Aged
  • Receptors, Tumor Necrosis Factor / therapeutic use
  • Remission Induction

Substances

  • Antirheumatic Agents
  • Immunoglobulin G
  • Receptors, Tumor Necrosis Factor
  • Captopril
  • Etanercept