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    J Neurol Sci. 1992 Mar;108(1):32-4.

    The association of astrocytoma and pituitary adenoma in a patient with alcaptonuria.

    Source

    Department of Endocrinology, University of Antwerp, Belgium.

    Abstract

    A female patient with a juvenile pilocytic astrocytoma and a pituitary adenoma is described. The patient also has alcaptonuria, a rare inborn error of metabolism with autosomal recessive mode of inheritance. The association of these three disorders has never been reported previously. The possible existence of a common genetic factor in the development of both tumors and alcaptonuria is discussed.

    PMID:
    1624949
    [PubMed - indexed for MEDLINE]

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