J Am Diet Assoc. 1992 Jul;92(7):844-50.

Review of L-tryptophan and eosinophilia-myalgia syndrome.

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Tyson & Associates, Hawthorne, Calif.

Abstract

The ingestion of L-tryptophan (LT)-containing products has recently been associated with a newly diagnosed disorder known as eosinophilia-myalgia syndrome (EMS). This article reviews the pertinent research concerning the association between LT-containing products and EMS, including (a) the incidence and clinical course of EMS; (b) characteristics (eg, age and sex) of patients with EMS; (c) LT intakes (eg, dose, duration of intake) associated with EMS; (d) tracing of implicated LT-containing products to one raw material manufacturer, (e) theories related to the association, for example, the contamination theory; and (f) regulatory issues surrounding LT-containing products. The importance of this information to the dietitian is twofold. First, because LT is an essential amino acid, questions concerning LT-containing products and EMS are often directed to dietitians. Second, dietitians should be aware of the association to help facilitate the identification and care of patients with EMS.

PMID:: 1624654; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

Tryptophan

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Medical

Eosinophilic Disorders - MedlinePlus Health Information

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(L)-TRYPTOPHAN - HSDB

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Related citations in PubMed

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