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Vaccine. 2006 Jan 23;24(4):476-84. Epub 2005 Aug 30.

Active telephone surveillance to evaluate adverse events among civilian smallpox vaccine recipients.

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  • 1National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Abstract

OBJECTIVE:

Better characterize and monitor adverse events following Dryvax vaccinia vaccination in civilian health care workers and other first responders.

DESIGN:

Telephone interviews to ascertain adverse events experienced.

RESULTS:

Eight hundred twenty-five vaccinees, including 44 in the comparison group, were interviewed. At 10 days, 71.4% reported blisters, 35.1% reported bumps at the vaccination site, 48.5% swelling, 47.3% scab, tiredness/lethargy/fatigue (43.6%), headache (34.2%), lymph node swelling/tenderness (28.5%), muscle pain (23.1%), chills (14.4%), joint pain 11.8%, and fever >100 degrees F (12.5%). The 12.5% reported missing work because of vaccine adverse events. Most adverse events were anticipated and of short duration.

PMID:
16216396
[PubMed - indexed for MEDLINE]
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