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Clin Otolaryngol. 2005 Aug;30(4):373-5.

Variability of vascularity in nasal mucosa as demonstrated by CD34 immunohistochemistry.

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  • 1Department of Otorhinolaryngology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, UK. carlphilpott@btopenworld.com


Regional anatomical variations in the nasal vasculature have not been studied histologically. Immunohistochemistry performed using marker for CD34 antigen on vascular endothelium biopsied from 5 sites on the lateral nasal wall and compared with one septal biopsy. No significant regional variations in microvascular architecture over the lateral wall of the nose were found. * Lateral wall measurements were significantly different to the septal measurements (P = 0.0003, 0.01). Suggests biopsies can be taken from any site on the lateral wall and give a representative sampling of the vascularity for research purposes.

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