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Genome Biol. 2005;6(10):235. Epub 2005 Sep 29.

Systems biology approaches in cell signaling research.

Author information

  • 1Division of Biochemistry and Molecular Biology, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3202, USA.

Abstract

The use of methods for global and quantitative analysis of cells is providing new systems-level insights into signal transduction processes. Recent studies reveal important information about the rates of signal transmission and propagation, help establish some general regulatory characteristics of multi-tiered signaling cascades, and illuminate the combinatorial nature of signaling specificity in cell differentiation.

PMID:
16207364
[PubMed - indexed for MEDLINE]
PMCID:
PMC1257459
Free PMC Article

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