Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Pediatr. 2005 Sep;147(3 Suppl):S69-72.

Sweat testing infants detected by cystic fibrosis newborn screening.

Author information

  • 1New England Newborn Screening Program of University of Massachusetts Medical School, MA 02130, USA. richard.parad@umassmed.edu

Abstract

OBJECTIVE:

Describe and define limitations of early pilocarpine iontophoresis (sweat testing) for cystic fibrosis (CF) newborn screening (NBS).

STUDY DESIGN:

Population-based results from follow-up of CF NBS-positive newborns.

RESULTS:

Insufficient quantity of sweat is more likely if the sweat test is done too early, but testing is generally successful after 2 weeks of age. Sweat chloride levels drop over the first weeks of life. CF carriers have higher sweat chloride concentrations than non-carriers.

CONCLUSIONS:

Sweat testing can be performed effectively after 2 weeks of age for CF NBS-positive newborns. Earlier testing has a higher risk of insufficient sweat for completing testing.

PMID:
16202787
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk