Splicing of a rare class of introns by the U12-dep...[Biol Chem. 2005]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 1

Click to change filter selection through MyNCBI.

1: Biol Chem. 2005 Aug;386(8):713-24. Links

Splicing of a rare class of introns by the U12-dependent spliceosome.

Will CL, Lührmann R.

Max Planck Institute for Biophysical Chemistry, Department of Cellular Biochemistry, Am Fassberg 11, D-37077 Göttingen, Germany. cwill1@gwdg.de

Pre-mRNA splicing is catalyzed by two unique spliceosomes, designated U2- or U12-dependent. In contrast to the well-characterized U2-dependent spliceosome, much remains to be learned about the less abundant U12-type spliceosome. This review focuses on recent advances in elucidating the structure and function of the minor U12-dependent spliceosome. Interesting similarities and differences between the U12- and U2-dependent spliceosomes are also highlighted.

PMID: 16201866 [PubMed - indexed for MEDLINE]

Branchpoint selection in the splicing of U12-dependent introns in vitro.
RNA. 2002 May; 8(5):579-86.

[RNA. 2002]
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns.
Science. 1996 Sep 27; 273(5283):1824-32.

[Science. 1996]
The divergent U12-type spliceosome is required for pre-mRNA splicing and is essential for development in Drosophila.
Mol Cell. 2002 Feb; 9(2):439-46.

[Mol Cell. 2002]
ReviewTowards understanding the catalytic core structure of the spliceosome.
Biochem Soc Trans. 2005 Jun; 33(Pt 3):447-9.

[Biochem Soc Trans. 2005]
ReviewAlternative splicing of U12-type introns.
Front Biosci. 2008 Jan 1; 13:1681-90. Epub 2008 Jan 1.

[Front Biosci. 2008]
» See reviews... | » See all...

Cited by 10 PubMed Central articles

Mutational analysis of the U12-dependent branch site consensus sequence.
Brock JE, Dietrich RC, Padgett RA. RNA. 2008 Nov; 14(11):2430-9. Epub 2008 Sep 29.

[RNA. 2008]
Where in the cell is the minor spliceosome?
Steitz JA, Dreyfuss G, Krainer AR, Lamond AI, Matera AG, Padgett RA. Proc Natl Acad Sci U S A. 2008 Jun 24; 105(25):8485-6. Epub 2008 Jun 17.

[Proc Natl Acad Sci U S A. 2008]
Minor spliceosome components are predominantly localized in the nucleus.
Pessa HK, Will CL, Meng X, Schneider C, Watkins NJ, Perälä N, Nymark M, Turunen JJ, Lührmann R, Frilander MJ. Proc Natl Acad Sci U S A. 2008 Jun 24; 105(25):8655-60. Epub 2008 Jun 16.

[Proc Natl Acad Sci U S A. 2008]
» See all...

Recent Activity

Clear Turn Off Turn On

Splicing of a rare class of introns by the U12-dependent spliceosome.Splicing of a rare class of introns by the U12-dependent spliceosome.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

Splicing of a rare class of introns by the U12-dependent spliceosome.

Related articles

Cited by 10 PubMed Central articles

Recent Activity