Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Aug;72(2 Pt 1):021910. Epub 2005 Aug 24.

Mode locking the cell cycle.

Source

The Rockefeller University, 1230 York Avenue, New York, New York, 10021, USA. fcross@mail.rockefeller.edu

Abstract

A characteristic property of nonlinear oscillatory systems is their ability to mode lock to a periodic, external, driving signal. In an n:m mode-locked state, the driven system executes n oscillations to every m oscillations of the driving signal, with a constant phase relationship between the two oscillations. We investigate mode locking for a mathematical model of the cell cycle in budding yeast. We determine which variables are most effective in coupling an external stimulus to the cell cycle oscillator, and speculate about whether experiments are feasible and informative for this model organism.

PMID:: 16196607; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Cell Cycle Proteins

Grant Support

GM47238/GM/NIGMS NIH HHS/United States

LinkOut - more resources

Full Text Sources

Other Literature Sources

Molecular Biology Databases

Saccharomyces Genome Database

Supplemental Content

Save items

Related citations in PubMed

A minimal mathematical model combining several regulatory cycles from the budding yeast cell cycle. [IET Syst Biol. 2007]
A minimal mathematical model combining several regulatory cycles from the budding yeast cell cycle.
Sriram K, Bernot G, Képès F. IET Syst Biol. 2007 Nov; 1(6):326-41.
Review Mathematical models of cell cycle regulation. [Brief Bioinform. 2005]
Review Mathematical models of cell cycle regulation.
Fuss H, Dubitzky W, Downes CS, Kurth MJ. Brief Bioinform. 2005 Jun; 6(2):163-77.
Deconvolving cell cycle expression data with complementary information. [Bioinformatics. 2004]
Deconvolving cell cycle expression data with complementary information.
Bar-Joseph Z, Farkash S, Gifford DK, Simon I, Rosenfeld R. Bioinformatics. 2004 Aug 4; 20 Suppl 1:i23-30.
Bifurcational mechanisms of synchronization of a resonant limit cycle on a two-dimensional torus. [Chaos. 2008]
Bifurcational mechanisms of synchronization of a resonant limit cycle on a two-dimensional torus.
Anishchenko V, Nikolaev S, Kurths J. Chaos. 2008 Sep; 18(3):037123.
Review The ups and downs of modeling the cell cycle. [Curr Biol. 2004]
Review The ups and downs of modeling the cell cycle.
Ingolia NT, Murray AW. Curr Biol. 2004 Sep 21; 14(18):R771-7.

See reviews... See all...

Cited by 1 PubMed Central article

A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells. [PLoS One. 2008]
A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells.
Charvin G, Cross FR, Siggia ED. PLoS One. 2008 Jan 23; 3(1):e1468. Epub 2008 Jan 23.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Mode locking the cell cycle.
Mode locking the cell cycle.
Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Aug ;72(2 Pt 1):021910. Epub 2005 Aug 24 .

PubMed
Towards an understanding of the arginine-aspartate interaction.
Towards an understanding of the arginine-aspartate interaction.
J Mol Biol. 1992 Jul 5 ;226(1):251-62.

PubMed
Passive seeding in metanephric adenoma: a review of pseudometastatic lesions in ...
Passive seeding in metanephric adenoma: a review of pseudometastatic lesions in perinephric lymph nodes.
Arch Pathol Lab Med. 2005 Oct ;129(10):1317-21.

PubMed
Expectations from structural genomics revisited: an analysis of structural genom...
Expectations from structural genomics revisited: an analysis of structural genomics targets.
Am J Pharmacogenomics. 2005 ;5(5):339-42.

PubMed
Prediction of gene structure.
Prediction of gene structure.
J Mol Biol. 1992 Jul 5 ;226(1):141-57.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: