Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Cancer Causes Control. 2005 Nov;16(9):1055-8.

Prostate cancer risk among men with diabetes mellitus (Spain).

Author information

  • 1Centro Español de Investigación Farmacoepidemiológica (CEIFE), Madrid, Spain. agonzalez@ceife.es

Abstract

OBJECTIVE:

Observational studies have associated diabetes with a decreased risk of prostate cancer. We aimed to evaluate this association using the General Practitioner Research Database in the UK.

METHODS:

Population based case-control study nested in a cohort.

RESULTS:

We identified 2,183 incident cases of prostate cancer between January 1995 and December 2001. We found that diabetic patients had a decreased risk of prostate cancer (OR = 0.72; 95% CI: 0.59-0.87). This association was observed among treated diabetics (OR = 0.63; 95% CI: 0.50-0.80) but not among untreated diabetics (OR = 1.01; 95% CI: 0.73-1.40). Our results suggest that the observed reduced risk could be restricted to users of insulin or sulphonylureas.

CONCLUSION:

Patients with diabetes have a decreased risk of prostate cancer. The role of antidiabetic treatment in this association warrants further research.

PMID:
16184470
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Write to the Help Desk