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Infect Immun. 2005 Oct;73(10):7040-2.

Protective role of neutrophils in mice experimentally infected with Rhodococcus equi.

Author information

  • 1Equine Infectious Disease Laboratory, Department of Large Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, 77843, USA. rmartens@cvm.tamu.edu

Abstract

Neutrophils are important in controlling early infections with the intracellular bacterium Rhodococcus equi. Antineutrophil monoclonal antibody (RB6-8C5)-induced neutrophil deficiency during the first week after experimental infection of mice with R. equi resulted in more severe disease and significantly increased tissue concentrations of R. equi.

PMID:
16177388
[PubMed - indexed for MEDLINE]
PMCID:
PMC1230988
Free PMC Article

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