Your browser version may not work well with NCBI's Web applications. More information here...
1: Brain Res Bull. 1992 Apr;28(4):637-9.Click here to read Links

Administration of satiety factors and gustatory responsiveness in the nucleus tractus solitarius of the rat.

Giza BK, Scott TR, Vanderweele DA.

Department of Psychology, University of Delaware, Newark 19716.

The administration of certain factors associated with postprandial satiety decreases gustatory responsiveness. We compared the effects of intravenous injections of glucose, insulin, pancreatic glucagon (PG), and cholecystokinin (CCK) on multiunit activity evoked from taste responsive neurons in the nucleus tractus solitarius of rats. Glucose, insulin, and PG reliably suppressed evoked responses to lingual application of 1.0M glucose, whereas responses that followed CCK remained unchanged. A common physiological consequence of glucose, insulin, and glucagon is increased glucose availability which may impact directly on gustatory neurons or indirectly through modifications in ventral forebrain or vagal afferent activity.

PMID: 1617448 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Glucagon (GlucaGen Diagnostic Kit® )

    Glucagon is a hormone produced in the pancreas. Glucagon is used to raise very low blood sugar. Glucagon is also used in diagnostic testing of the stomach and other digestive organs.

  • Insulin Injection (Humulin R® , Humulin N® , Humulin 70/30® , ...)

    Insulin injection is used to control blood sugar in people who have type 1 diabetes (condition in which the body does not make insulin and therefore cannot control the amount of sugar in the blood) or in people who have ...

  • Source: AHFS Consumer Medication Information