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Genome Res. 2005 Oct;15(10):1456-61. Epub 2005 Sep 16.

The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species.

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  • 1Department of Genetics, Smurfit Institute, University of Dublin, Trinity College, Dublin 2, Ireland.


We developed the Yeast Gene Order Browser (YGOB; http://wolfe.gen.tcd.ie/ygob) to facilitate visual comparisons and computational analysis of synteny relationships in yeasts. The data presented in YGOB, currently covering seven species, are based on sets of homologous genes that have been intensively manually curated based on both sequence similarity and genomic context (synteny). We reconciled different laboratories' lists of paralogous Saccharomyces cerevisiae gene pairs formed by genome duplication (ohnologs), and present near-exhaustive lists of the ohnolog pairs retained in S. cerevisiae (551, including 22 previously unidentified), Saccharomyces castellii (599), and Candida glabrata (404).

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