Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Retrovirology. 2005 Sep 19;2:56.

Valproic acid and HIV-1 latency: beyond the sound bite.

Author information

  • Department of Medicine, Saint Michael's Medical Center, The New Jersey Medical School, Newark, New Jersey 07102, USA. ssmith1824@aol.com

Abstract

A recent publication in Lancet by Dr. David Margolis and colleagues raised the prospect that HIV infection may be curable. In this pilot study, which received much attention from the press, Dr. Margolis'group found that valproic acid plus enfuvirtide reduces the pool of CD4+ T-cells, which are latently infected with HIV-1, the so-called viral reservoir. This commentary critically addresses current data on this topic.

PMID:
16168066
[PubMed - indexed for MEDLINE]
PMCID:
PMC1242254
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Write to the Help Desk