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J Fluoresc. 2005 Jul;15(4):569-84.

Emerging applications of phosphorescent metalloporphyrins.

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  • 1Biochemistry Department/ABCRF, University College Cork, College Road, Cork, Ireland. d.papokovsky@ucc.ie

Abstract

The subject of phosphorescent metalloporphyrins is reviewed, focusing mainly on the development and application of Pt- and Pd-porphyrins. A summary of their general chemical and photophysical properties, and guidelines for rational design of the phosphorescent labels, bioconjugates and probes is given. Examples of different detection formats and particular bio-analytical applications developed in recent years are presented. The potential of phosphorescent porphyrin label methodology is discussed and compared to that of the long-decay fluorescent lanthanide chelates and other common fluorophores.

PMID:
16167215
[PubMed - indexed for MEDLINE]
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