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Am J Surg. 2005 Oct;190(4):595-7.

Staged sentinel lymph node biopsy before mastectomy facilitates surgical planning for breast cancer patients.

Author information

  • 1Division of Surgical Oncology, University of North Carolina at Chapel Hill, 3010 Old Clinic Bldg., CB No. 7213, Chapel Hill, NC 27599, USA. nancy_demore@med.unc.edu

Abstract

BACKGROUND:

In patients with breast cancer who choose mastectomy with immediate reconstruction, the sentinel lymph node (SLN) status on permanent histology may complicate treatment if a metastasis is found. The purpose of this study was to determine how performing an SLN biopsy (SLNB) before the definitive operation would influence subsequent surgical procedures.

METHODS:

Our SLN database was searched for patients who underwent staged SLNB with subsequent mastectomy between 2001 and 2004.

RESULTS:

Twenty-five patients with 27 breast cancers underwent SLNB before mastectomy. Of them, 9 of 27 (33%) were node positive. All 9 patients underwent modified radical mastectomy. Three node-positive patients did not undergo immediate reconstruction. Of the remaining 6 node-positive patients, 5 underwent reconstruction with autologous tissue rather than a tissue expander. In contrast, 6 of 16 (37%) node-negative patients underwent reconstruction with a tissue expander.

CONCLUSIONS:

Staged SLNB assists in selecting the appropriate operation in patients who are considering immediate reconstruction.

PMID:
16164929
[PubMed - indexed for MEDLINE]
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