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[Protective effects of astragali injection on tubular in patients with primary nephrotic syndrome].

[Article in Chinese]

Author information

  • 1Department of Nephrology, Xiangya Hospital, Central South University, Changsha, China. xyclp@medmail.com.cn

Abstract

OBJECTIVE:

To determine the effects of astragali injection on tubular and its possible mechanisms.

METHODS:

Sixty patients with primary nephritic syndrome (PNS) were randomly divided into astragali group (n = 30) and control group (n = 30). The surm albumin (sALB) and urinary excretion of retinol-binding protein (RBP), N-Acety-P-beta-Glucosaminidase (NAG), beta2- Microglobulin (beta2MG) were measured before and after the treatment.

RESULTS:

After the one month treatment, sALB was significantly higher, and ubeta2MG, uNAG, uRBP, and 24 huP were significantly lower in astragali group (P <0.01, P < 0.05).

CONCLUSION:

Astragali injection on tubular plays a protective role in PNS.

PMID:
16145898
[PubMed - indexed for MEDLINE]
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