Abstract

OBJECTIVES:

Pathogenesis of pregnancy induced hypertension and intrauterine growth retardation is strictly connected with poor supply of the feto-maternal unit with well oxygenated blood rich in all nutritional substances. Monitoring of the pregnancy course and normal values estimation in the group of non-complicated pregnancies allows us to get PIH and IUGR prediction values of the uterine velocimetry.

DESIGN:

Main aims of the study were: estimation of the normal values for utcrine velocimetry in II and III trimester of pregnancy (S/D, RI, and PI); analysis of the prognostic usefulness of these parameters (between 20-24 gestation weeks) and importance of notch in FVW for development of PIH and IUGR later in pregnancy.

RESULTS:

We observed a decrease of uterine velocimetry parameters (mean values) in the course of normal pregnancy (19-40 gestation weeks). The sensitivity of the notch observation in 20-24 week in the uterine FVW for the prediction of PIH and/or IUGR (all study group) in the III trimester was 73,68% and the specificity 97,15%. The prognostic value of the examined pathology markers at 20-24 weeks was for notch or R >90% - 79,69% and notch or PI >90% - 70,31%.

CONCLUSIONS:

Normal pregnancy is characterized by a decrease of the uterine S/D, RI and PI values. There is a significant dependence between high values of S/D, RI, PI and observation of notch in uterine FVW at 20-24 weeks and development of PIH and IUGR in the course of pregnancy. Doppler velocimetry of the uterine blood flow as a screening method at 20-24 weeks allows to get a prognosis about further course of pregnancy in the groups of low- and high-risk for PIH and IUGR development.