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Clin Infect Dis. 2005 Oct 1;41(7):1053-6. Epub 2005 Aug 30.

HIV controllers: a homogeneous group of HIV-1-infected patients with spontaneous control of viral replication.

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  • 1INSERM E-0109, Faculté de Médecine Paris-Sud, Université Paris XI, Service de Santé Publique, Bicêtre, France.

Erratum in

  • Clin Infect Dis. 2005 Dec 1;41(11):1694.
  • Clin Infect Dis. 2005 Sep 15;41 Suppl 6:1694.


We identified a total 15 patients who have maintained undetectable plasma HIV RNA loads without antiretroviral treatment for >10 years from cohorts of 1300 and 1551 patients infected with human immunodeficiency virus (HIV). These 15 patients, whom we have referred to as "HIV controllers," are characterized by a low HIV DNA load in peripheral blood mononuclear cells and by a strong HIV-specific immune response.

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