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    Am J Emerg Med. 2005 Sep;23(5):696-703.

    Premature atherosclerosis and acute coronary syndrome in systemic lupus erythematosus.

    Source

    Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. amattu@smail.maryland.edu

    Abstract

    Systemic lupus erythematosus (SLE) is a vasculitic disorder with potential for multisystem organ dysfunction. Among the organ systems affected is the cardiovascular system. Patients with SLE are prone to premature atherosclerosis; this premature atherosclerosis places the patient at risk for myocardial infarction with onset at a relatively young age. We present 4 patients with SLE who experienced myocardial infarction; these patients also experienced diagnostic and treatment delays because of their relatively young age at presentation. Relevant pathophysiology and diagnostic strategies are discussed.

    PMID:
    16140181
    [PubMed - indexed for MEDLINE]

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