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1: IDrugs. 1999 Aug;2(8):802-6.Links

HP-228 (Trega Biosciences Inc).

Wilkison WO.

Zen Bio Inc, 3200 Chapel Hill-Nelson Blvd, Suite 102, PO Box 12503, Research Triangle Park, NC 27709, USA. zenbio@mindspring.com

HP-228 is a cytokine regulating agent from Trega Biosciences (formerly Houghten Pharmaceuticals). It is in phase II trials for the management of post-surgical pain and inflammation [195065]. The drug was indicated for the treatment of diabetes, obesity and chemotherapy-induced toxicity, but Trega has decided to discontinue the development of HP-228 for these indications [259339].

PMID: 16127656 [PubMed]

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