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J Pediatr. 2005 Aug;147(2):263-6.

The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds.

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  • 1University of Texas Southwestern Medical Center, Department of Pediatrics, Macalester College, St. Paul, Minnesota, USA.


Hepatoblastoma is associated with familial adenomatous polyposis (FAP). In a series of 93 patients with hepatoblastoma,8 (8.6%) reported family histories suggestive of FAP. These and a review of reported FAP kindreds with hepatoblastoma may provide information helpful in counseling families with FAP.

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