Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Lancet. 2005 Aug 27-Sep 2;366(9487):763-73.

Health risks and benefits of bis(4-chlorophenyl)-1,1,1-trichloroethane (DDT).

Author information

  • 1Epidemiology Branch, US National Institute of Environmental Health Sciences, P O Box 12233, Research Triangle Park, NC 27709, USA. rogan@niehs.nih.gov

Abstract

DDT (bis[4-chlorophenyl]-1,1,1-trichloroethane) is a persistent insecticide that was used worldwide from the mid 1940s until its ban in the USA and other countries in the 1970s. When a global ban on DDT was proposed in 2001, several countries in sub-Saharan Africa claimed that DDT was still needed as a cheap and effective means for vector control. Although DDT is generally not toxic to human beings and was banned mainly for ecological reasons, subsequent research has shown that exposure to DDT at amounts that would be needed in malaria control might cause preterm birth and early weaning, abrogating the benefit of reducing infant mortality from malaria. Historically, DDT has had mixed success in Africa; only the countries that are able to find and devote substantial resources towards malaria control have made major advances. DDT might be useful in controlling malaria, but the evidence of its adverse effects on human health needs appropriate research on whether it achieves a favourable balance of risk versus benefit.

Comment in

  • Risks and benefits of DDT. [Lancet. 2005]
PMID:
16125595
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk