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Chem Biol. 2005 Aug;12(8):859-60.

Deep sea mining for unique biocatalysts.

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  • Institute of Chemistry and Biochemistry, Department of Technical Chemistry and Biotechnology, Greifswald University, 17487 Greifswald, Germany. uwe.bornscheuer@uni-greifswald.de

Abstract

In this issue of Chemistry and Biology, Ferrer and coworkers describe the discovery of five esterases from a distinct deep sea hypersaline biotope. Interestingly, one enzyme has two unique features-it contains three active centers mediating distinct esterolytic activities, and its tertiary/quaternary structure can be modulated by environmental changes.

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PMID:
16125094
[PubMed - indexed for MEDLINE]
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