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    J Nat Prod. 2005 Aug;68(8):1300-2.

    Aspirochlorine class compounds from Aspergillus flavus inhibit azole-resistant Candida albicans.

    Source

    Natural Products Support Group, SAIC-Frederick, Inc., Bldg 431, FCRDC, Frederick, Maryland 21702-1201, USA.

    Abstract

    Dereplication of the antifungal extracts of Aspergillus flavus indicated that the primary antifungal compound present was the known aspirochlorine (1). Preparative isolation work resulted in the identification of the new compounds tetrathioaspirochlorine (2) and cyclo(D-N-methyl-Leu-L-Trp) (3).

    PMID:
    16124785
    [PubMed - indexed for MEDLINE]

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