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    J Nat Prod. 2005 Aug;68(8):1300-2.

    Aspirochlorine class compounds from Aspergillus flavus inhibit azole-resistant Candida albicans.

    Klausmeyer P, McCloud TG, Tucker KD, Cardellina JH 2nd, Shoemaker RH.

    Natural Products Support Group, SAIC-Frederick, Inc., Bldg 431, FCRDC, Frederick, Maryland 21702-1201, USA.

    Dereplication of the antifungal extracts of Aspergillus flavus indicated that the primary antifungal compound present was the known aspirochlorine (1). Preparative isolation work resulted in the identification of the new compounds tetrathioaspirochlorine (2) and cyclo(D-N-methyl-Leu-L-Trp) (3).

    PMID: 16124785 [PubMed - indexed for MEDLINE]

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