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1: Southeast Asian J Trop Med Public Health. 2005 May;36(3):650-2.Links

Double-dose ivermectin vs albendazole for the treatment of gnathostomiasis.

Nontasut P, Claesson BA, Dekumyoy P, Pakdee W, Chullawichit S.

Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

A comparative study was performed for the treatment of gnathostomiasis patients with ivermectin 0.2 mg/kg for 2 days in 15 patients vs albendazole 400 mg twice daily for 21 days in 14 patients. The ivermectin and albendazole gave cure rates of 100% and 78.5%, respectively, however the difference was not statistically significant between the two drugs (Fisher's exact, p=0.0996). One year after treatment, the patients who had no migratory swellings and a drop in ELISA titers or a negative immunoblot test were considered to be cured. The side effect of ivermectin for two days was dizziness. The side effects of albendazole were nausea, dizziness, and an increased alkaline phosphatase.

PMID: 16124432 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Ivermectin (Stromectol® )

    Ivermectin is used to treat strongyloidiasis (threadworm; infection with a type of roundworm that enters the body through the skin, moves through the airways and lives in the intestines). Ivermectin is also used to contr...

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