Orthopedics. 2005 Jul;28(7):651-4.

The paradox of heparin-induced thrombocytopenia: future anticoagulation.

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University of Kentucky Chandler Medical Center, Lexington, Ky, USA.

Abstract

Heparin and low molecular weight heparin agents are frequently administered to postoperative orthopedic patients. In patients with a history of heparin-induced thrombocytopenia, alternative anticoagulant agents to heparin for prophylaxis and treatment must be considered. Unfortunately, the data is limited in this patient population. Upon transitioning from heparin-induced thrombocytopenia treatment with direct thrombin inhibitors, argatroban, or lepirudin, careful consideration must be taken to avoid further thrombotic complications.

PMID:: 16119279; [PubMed - indexed for MEDLINE]

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Cited by 1 PubMed Central article

The Pharmacotherapy of Heparin-Induced Thrombocytopenia (HIT) : A Review of Contemporary Therapeutic Challenges in Clinical Practice. [Malays J Med Sci. 2008]
The Pharmacotherapy of Heparin-Induced Thrombocytopenia (HIT) : A Review of Contemporary Therapeutic Challenges in Clinical Practice.
Hassan Y, Awaisu A, Al-Meman AA, Aziz NA. Malays J Med Sci. 2008 Apr; 15(2):3-13.

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