Appl Biochem Biotechnol. 2005 Aug;126(2):79-92.

Surface plasmon resonance: applications in understanding receptor-ligand interaction.

Source

Virology Division, Defence Research and Development Establishment, Jhansi Road, Gwalior 474 002 India. ppat@rediffmail.com

Abstract

During last decade there has been significant progress in the development of analytical techniques for evaluation of receptor-ligand interaction. Surface plasmon resonance (SPR)-based optical biosensors are now being used extensively to define the kinetics of wide variety of macromolecular interactions and high- and low-affinity small molecule interactions. The experimental design data analysis methods are evolving along with widespread applications in ligand fishing, microbiology, virology, host-pathogen interaction, epitope mapping, and protein-, cell-, membrane-, nucleic acid-protein interactions. SPR-based biosensors have strong impact on basic and applied research significantly. This brief review describes the SPR technology and few of its applications in relation to receptor-ligand interaction that has brought significant change in the methodology, analysis, interpretation, and application of the SPR technology.

PMID:: 16118464; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

Ligands

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Supplemental Content

Save items

Related citations in PubMed

Review Spying on HIV with SPR. [Trends Microbiol. 2003]
Review Spying on HIV with SPR.
Rich RL, Myszka DG. Trends Microbiol. 2003 Mar; 11(3):124-33.
Review Surface plasmon resonance: towards an understanding of the mechanisms of biological molecular recognition. [Curr Opin Chem Biol. 2001]
Review Surface plasmon resonance: towards an understanding of the mechanisms of biological molecular recognition.
McDonnell JM. Curr Opin Chem Biol. 2001 Oct; 5(5):572-7.
Review Advances in surface plasmon resonance biosensor analysis. [Curr Opin Biotechnol. 2000]
Review Advances in surface plasmon resonance biosensor analysis.
Rich RL, Myszka DG. Curr Opin Biotechnol. 2000 Feb; 11(1):54-61.
Review Interaction analysis of viral cytokine-binding proteins using surface plasmon resonance. [Methods Mol Biol. 2004]
Review Interaction analysis of viral cytokine-binding proteins using surface plasmon resonance.
Seet BT, McFadden G. Methods Mol Biol. 2004; 269:219-42.
Review Present and future of surface plasmon resonance biosensors. [Anal Bioanal Chem. 2003]
Review Present and future of surface plasmon resonance biosensors.
Homola J. Anal Bioanal Chem. 2003 Oct; 377(3):528-39. Epub 2003 Jul 19.

See reviews... See all...

Cited by 6 PubMed Central articles

A triad of lys12, lys41, arg78 spatial domain, a novel identified heparin binding site on tat protein, facilitates tat-driven cell adhesion. [PLoS One. 2008]
A triad of lys12, lys41, arg78 spatial domain, a novel identified heparin binding site on tat protein, facilitates tat-driven cell adhesion.
Ai J, Xin X, Zheng M, Wang S, Peng S, Li J, Wang L, Jiang H, Geng M. PLoS One. 2008; 3(7):e2662. Epub 2008 Jul 16.
A surface plasmon resonance sensor for the detection of deoxynivalenol using a molecularly imprinted polymer. [Sensors (Basel). 2011]
A surface plasmon resonance sensor for the detection of deoxynivalenol using a molecularly imprinted polymer.
Choi SW, Chang HJ, Lee N, Chun HS. Sensors (Basel). 2011; 11(9):8654-64. Epub 2011 Sep 5.
Scientific considerations for generic synthetic salmon calcitonin nasal spray products. [AAPS J. 2011]
Scientific considerations for generic synthetic salmon calcitonin nasal spray products.
Lee SL, Yu LX, Cai B, Johnsons GR, Rosenberg AS, Cherney BW, Guo W, Raw AS. AAPS J. 2011 Mar; 13(1):14-9. Epub 2010 Oct 30.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Surface plasmon resonance: applications in understanding receptor-ligand interac...
Surface plasmon resonance: applications in understanding receptor-ligand interaction.
Appl Biochem Biotechnol. 2005 Aug ;126(2):79-92.

PubMed
Endoscopic ultrasound added to mediastinoscopy for preoperative staging of patie...
Endoscopic ultrasound added to mediastinoscopy for preoperative staging of patients with lung cancer.
JAMA. 2005 Aug 24 ;294(8):931-6.

PubMed
Naltrexone treatment for alcohol dependency.
Naltrexone treatment for alcohol dependency.
JAMA. 2005 Aug 24 ;294(8):899-900; author reply 900.

PubMed
Buprenorphine for office-based treatment of patients with opioid addiction.
Buprenorphine for office-based treatment of patients with opioid addiction.
J Am Osteopath Assoc. 2005 Jun ;105(6 Suppl 3):S8-13.

PubMed
Beneficial effect of a low glycaemic index diet in type 2 diabetes.
Beneficial effect of a low glycaemic index diet in type 2 diabetes.
Diabet Med. 1992 Jun ;9(5):451-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: