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Mol Cell. 2005 Aug 19;19(4):431-2.

TPX or not TPX?

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  • 1Cell Biology and Biophysics Program, European Molecular Biology Laboratory, Heidelberg, Germany.


An Aurora A regulatory module has been identified in two different proteins: TPX2 in Xenopus laevis and TPXL-1 in C. elegans. The diverse roles of these two proteins in spindle assembly leave us to beckon the true C. elegans TPX2 ortholog to center stage.

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