Format

Send to:

Choose Destination
See comment in PubMed Commons below
Nature. 2005 Aug 18;436(7053):961-6.

Prospects for a vaccine against the hepatitis C virus.

Author information

  • 1Chiron Corporation, 4560 Horton Street, Emeryville, California 94608, USA. michael_houghton@chiron.com

Abstract

The recent discovery of natural immunity to the hepatitis C virus and vaccine efficacy in the chimpanzee challenge model has allowed optimism about the development of at least a partly effective vaccine against this heterogeneous pathogen that is responsible for much of the chronic liver disease around the world. The immune systems of some infected individuals can spontaneously clear the virus, whereas other people need treatment with antivirals that work partly by stimulating humoral and cellular immune responses. Therefore, therapeutic vaccine strategies are also being pursued to improve treatment outcome.

PMID:
16107836
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Write to the Help Desk