Format

Send to:

Choose Destination
See comment in PubMed Commons below
Pediatr Blood Cancer. 2006 Nov;47(6):851-4.

Familial adenomatous polyposis in two brothers with hepatoblastoma: implications for diagnosis and screening.

Author information

  • 1Department of Hematology/Oncology, St Jude Children's Research Hospital, Memphis, TN 38105, USA.

Abstract

Two brothers with hepatoblastoma were noted to have a family history of early onset colon cancer. Genetic testing of the younger brother revealed a deletion in exon 15 of the adenomatous polyposis coli (APC) gene (2710-2711delAG), consistent with a diagnosis of familial adenomatous polyposis (FAP). We review the clinical and molecular aspects of the relationship between hepatoblastoma and FAP, and the implications for diagnostic testing and cancer screening in affected patients.

(c) 2005 Wiley-Liss, Inc.

PMID:
16106429
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for John Wiley & Sons, Inc.
    Loading ...
    Write to the Help Desk