Hypertens Res. 2005 Mar;28(3):191-202.

Hypertensive heart disease.

Source

Division of Cardiology, Long Island Jewish Hospital, New Hyde Park, New York 10040, USA. jdiamond@lij.edu

Abstract

Left ventricular hypertrophy (LVH) and diastolic dysfunction (CHF-D) are the early manifestations of cardiovascular target organ damage in patients with arterial hypertension and signify hypertensive heart disease. Identification of hypertensive heart disease is critical, as these individuals are more prone to congestive heart failure, arrhythmias, myocardial infarction and sudden cardiac death. Regression of left ventricular (LV) mass with antihypertensive therapy decreases the risk of future cardiovascular events. The goal of antihypertensive therapy is to both lower blood pressure (BP) and interrupt BP-independent pathophysiologic processes that promote LVH and CHF-D. The purpose of this review is to summarize current and emerging approaches to the pathophysiology and treatment of hypertensive heart disease.

PMID:: 16097361; [PubMed - indexed for MEDLINE]

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Review

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Antihypertensive Agents

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Cited by 4 PubMed Central articles

Body Mass Index or Microalbuminuria, Which One is More Important for the Prediction and Prevention of Diastolic Dysfunction in Non-diabetic Hypertensive Patients? [Int J Prev Med. 2012]
Body Mass Index or Microalbuminuria, Which One is More Important for the Prediction and Prevention of Diastolic Dysfunction in Non-diabetic Hypertensive Patients?
Shemirani H, Khosravi A, Hemmati R, Gharipour M. Int J Prev Med. 2012 Mar; 3(3):211-20.
Immediate response of myocardium to pressure overload includes transient regulation of genes associated with mitochondrial bioenergetics and calcium availability. [Genet Mol Biol. 2010]
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Deckmann AC, Theizen TH, Medrano FJ, Franchini KG, Pereira GA. Genet Mol Biol. 2010 Jan; 33(1):12-6. Epub 2010 Mar 1.
Differential effect of elevated blood pressure on left ventricular geometry types in black and white young adults in a community (from the Bogalusa Heart Study). [Am J Cardiol. 2011]
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