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J Occup Environ Med. 2005 Aug;47(8):806-16.

Insect repellents, phenoxyherbicide exposure, and non-Hodgkin's lymphoma.

Author information

  • 1Institute of Agricultural Rural and Environmental Health, University of Saskatchewan, Saskatoon, SK, S7N 0W8, Canada. mcduffie@sask.usask.ca

Abstract

OBJECTIVE:

We sought to test a hypothetical explanation of contradictory results in studies of phenoxyherbicides and NHL, that the exposure of rubber gloves recommended for use by farmers when mixing or applying pesticides simultaneously to 2,4-D (2,4-dichlorophenoxyacetic acid), DEET (N,N-diethyl-m-toluamide), and ultraviolet rays increased their permeability to 2,4-D.

METHODS:

We conducted a case (NHL n = 513)/control (n = 1506) study among men using age; province of residence; exposure to insect repellents containing DEET, phenoxy-herbicides, or dicamba; and gloves when handling pesticides.

RESULTS:

Using conditional logistic regression, the stratum with reported exposure to mecoprop, to DEET and the use of rubber gloves had higher odds ratios (3.86; 95% confidence interval = 1.57-9.49) compared with strata with other combinations.

CONCLUSIONS:

In conclusion, the etiologic complexity of NHL was demonstrated.

PMID:
16093930
[PubMed - indexed for MEDLINE]
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